TACC

Understanding brain plasticity in childhood: Graziella Di Cristo

Published on 10/06/2025

Graziella Di Cristo

Graziella Di Cristo is a Professor in the Department of Neurosciences at Université de Montréal and Head Co-Deputy of the Brain and Child Development Research Axis at CHU Sainte-Justine. She has been a TACC member since its launch in 2017.

Her research investigates the molecular and cellular mechanisms that guide the development of inhibitory neural circuits in the brain, focusing on how experience during critical periods of plasticity can strengthen learning and introduce vulnerability. 

As she explains, “the brain of a child is so much more plastic, so different from ours — a time when experience can shape development but also create great vulnerability.” 

By better understanding these processes, her work aims to reduce the impact of sensory dysfunctions and contribute to improving the lives of children and their families.

The extraordinary plasticity of children’s brains: Dr. Graziella Di Cristo reflects on how early sensory experiences shape development, create vulnerability, and open opportunities for intervention. (Production: Aura Strategies)

What sparked your interest in neurodevelopmental research?

Di Cristo: My interest in neurodevelopmental research is sparked by the wonder I still feel when I see children acquiring new skills with such a fast pace.

What motivates you?

Di Cristo: The brain is such a fascinating mystery. 

Studying it requires seeing things from different perspectives, learning always new methods and working in teams and with collaborators. It is never boring!

Why did you become a member of TACC?

Di Cristo: I became a member of TACC because its goal is to put together individuals with different perspectives and backgrounds. 

I believe this diversity of knowledge, ideas and lived experiences can move research forward.

Stay connected

To learn more about Dr. Di Cristo’s work, you can explore her Université de Montréal profile, her NCBI publication list, or connect with her on LinkedIn.